Qalabka ka saarida EtEraser™ SE Endotoxin

Qalabka ka saarida EtEraser™ SE Endotoxin

1. Macluumaadka alaabta

Lipopolysaccharide (LPS) waa endotoxin bakteeriyada iyo qayb weyn oo ka mid ah darbiyada unugga ee bakteeriyada granegative.Borotiinka dib-u-dhaqaajinta ee E.coli wuxuu ka kooban yahay heer sare oo endotoxins ah.Ka saarida kuwanendotoxins aad ayey lagama maarmaan u tahay hababka hoose.

Qalabka saarista EtEraser SE Endotoxinwaxaa loogu talagalay in laga saaro wasakheynta endotoxin ee xalalka aqueous.Xirmooyinka ka kooban xuubka ka saarista endotoxin wuxuu xidhaa si loo yareeyo heerarka endotoxin ee muunada borotiinka ≥99% in ka yar 2 saacadood.

Xirmada waxaa ku jira tiir ka saarista endotoxin horay loo sii diyaariyey, 1.5 ml, Equilibration Buffer, Regeneration Buffer iyo tuubada ururinta xorta ah ee pyrogen iyo talooyin.Tiirku waxa uu leeyahay awood xidhid sare ah>2,000,000 EU/ml.Alaabtan waxa laga yaabaa in dib loo isticmaalo ilaa shan jeer haddii si habboon loo soo cusboonaysiiyo.Xabagta affinity waxa lagu heli karaa slurry waxaana laga yaabaa inay kor u kacdo habka biopharmaceutical.

Qalabka saarista EtEraser SE Endotoxinka faa'idaysato heerka cuntada ee la bedelayε-poly-L-lysineligand ashigh affinity ligand ee endotoxins.Xabagta waa kuul agarose ah oo aad u xasiloon oo aan wax saamayn ah oo cytotoxic ah ku yeelan jidhka bini'aadamka.Nadiifinta ka dib, ma jiri doonto hadhaa sun ah oo ku hadhay shaybaarada.Tanixirmada ka saarista endotoxinwaxaa loo isticmaali karaa daawooyinka borotiinka, tallaalada, unugyada difaaca jirka, DNA/RNA, polysaccharide iyo muunado kale oo bayooloji ah.

2. Tilmaamaha alaabta

• xasillooni sare - ma saamayso dhaqdhaqaaqa inta badan muunada nafleyda

• Awood xidhidh sare ->2000000 EU/ml

• aan sun ahayn —–> Isku xidhka heerka cuntada aan sunta ahayn, wax cytotoxic ah ma laha poly lysine

• Soo kabashada borotiinka sare -> 95% soo kabashada borotiinka ee muunadaha borotiinka

Waxtarka sare ee saarista - ka saar> 99% endotoxin, heerka endotoxin ee muunada wuxuu noqon karaa wax ka yar 0.1 EU/ml ka dib habka ka saarista endotoxin

Kala duwanaansho codsi oo ballaaran - waxaa loo isticmaali karaa ka saarida endotoxin ee borotiinnada, peptides, unugyada difaaca jirka, tallaalada, polysaccharides iyo shaybaarrada kale ee nafleyda